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Synthesis
of Polypeptide Based Rod-Coil Block Copolymers
| Controlled
radical polymerization |
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N-Carboxyanhydride
(NCA) polymerization for preparation of polypeptides |
- Atom Transfer Radical Polymerization
- Reversible Addition/Fragmentation Chain
Transfer Polymerization
- Nitroxide mediated Polymerization |
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- Amin initiated NCA polymerization
- Nickel catalysed NCA polymerization,
developed by DEMING |
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Combination of two transition metal catalysed polymerisation
to produce well-defined rod coil block copolymers
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| Microphase
separation due to different domains of the blocks |
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Self
assembly of block copolymers into
ordered periodic structures |
Application:
drug carrier
|
Example
for self-assembling
G.
Floudas, H.-A. Klok et al., Macromolecules 2003, 36, 3673.
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